By the end of this section, you will be able to:
Define population genetics and describe how population genetics is used in the study of the evolution of populations
Define the Hardy-Weinberg principle and discuss its importance
By the end of this section, you will be able to:Describe the different types of variation in a populationExplain why only heritable variation can be acted upon by natural selectionDescribe genetic drift and the bottleneck effectExplain how each evolutionary force can influence the allele frequencies of a population
By the end of this section, you will be able to:
Explain pharmacogenomics
Define polygenic
By the end of this section, you will be able to:
Describe gel electrophoresis
Explain molecular and reproductive cloning
Describe uses of biotechnology in medicine and agriculture
By the end of this section, you will be able to:
Explain systems biology
Describe a proteome
Define protein signature
By the end of this section, you will be able to:
Define genomics
Describe genetic and physical maps
Describe genomic mapping methods
I am making some changes to this module, but I am not publishing By the end of this section, you will be able to:Describe three types of sequencingDefine whole-genome sequencing
By the end of this section, you will be able to:
Explain how the structure of DNA reveals the replication process
Describe the Meselson and Stahl experiments
By the end of this section, you will be able to:
Discuss the different types of mutations in DNA
Explain DNA repair mechanisms
By the end of this section, you will be able to:
Discuss the similarities and differences between DNA replication in eukaryotes and prokaryotes
State the role of telomerase in DNA replication
By the end of this section, you will be able to:
Explain the process of DNA replication in prokaryotes
Discuss the role of different enzymes and proteins in supporting this process
By the end of this section, you will be able to:
Describe the structure of DNA
Explain the Sanger method of DNA sequencing
Discuss the similarities and differences between eukaryotic and prokaryotic DNA
By the end of this section, you will be able to:
Explain transformation of DNA
Describe the key experiments that helped identify that DNA is the genetic material
State and explain Chargaff’s rules
By the end of this section, you will be able to:
Describe how changes to gene expression can cause cancer
Explain how changes to gene expression at different levels can disrupt the cell cycle
Discuss how understanding regulation of gene expression can lead to better drug design
By the end of this section, you will be able to:
Explain the process of epigenetic regulation
Describe how access to DNA is controlled by histone modification
By the end of this section, you will be able to:
Understand RNA splicing and explain its role in regulating gene expression
Describe the importance of RNA stability in gene regulation
By the end of this section, you will be able to:
Discuss the role of transcription factors in gene regulation
Explain how enhancers and repressors regulate gene expression
By the end of this section, you will be able to:
Understand the process of translation and discuss its key factors
Describe how the initiation complex controls translation
Explain the different ways in which the post-translational control of gene expression takes place